CSF3 and infection: As shown in Fig 7, CD-1 mice, but not B6 mice, showed statistically significantly elevated levels of G-CSF at days 6 and 10, as well as significantly high levels of cytokines and chemokines at day 10 (IFNγ, TNFα, Eotaxin/CCL1, MIP-1α/CCL3, MIP-1β/CCL4, RANTES/CCL5), implying high levels of proinflammatory responses at the late stages of infection in CD-1 mice.