AHNAK2 and in situ carcinoma: Likewise, AHNAK2 protein expression was found in pT2/T3 tumors of optimal cutting temperature compound and subsequently frozen samples.27 Another study using the Fourier transform infrared imaging had proven that AHNAK2 immunohistochemical expression could distinguish reactive urothelial atypia from carcinoma in situ, with a sensitivity of 97% and a specificity of 69%.