VCAM1 and acute kidney injury: To screen feasible molecular targets for EC‐specific binding, we first examined the gene expression of several adhesion molecules (including Selp, Sele, Icam1, Vcam1, and Pecam1) in kidneys that are mainly responsible for leukocyte capture in the early stages of AKI.[4d] We found that the expression levels of Selp, Sele, and Icam1 were markedly increased in renal tissues after severe IRI, and the expression of Selp was the highest (Figure 1a).