BIRC2 and acute lymphoblastic leukemia: In line with the findings that SM mainly targeted cIAP‐1/2 and induced apoptosis dependent on TNFα signaling and/or formation of the ripoptosome (Petersen et al, 2007; Varfolomeev et al, 2007; Vince et al, 2007; Tenev et al, 2011; Loder et al, 2012; Belz et al, 2014), we have previously shown that cIAP‐1/2 are important when SM‐sensitized SM‐sensitive REH ALL cells towards cytotoxic drugs (Loder et al, 2012).