XIAP and acute lymphoblastic leukemia: Using lentiviruses (Terziyska et al, 2012), PDX ALL cells were molecularly modified identically as NALM‐6 cells (Fig 5A), and dsRED expression was analyzed to verify similar shRNA expression in sh‐CTRL and sh‐XIAP cells (Fig EV3A); after each transduction, transgenic PDX r/r ALL cells were enriched by flow cytometry and re‐amplified in mice (Fig 5A).