Combination with tumour necrosis factor (TNF): Similar to the previous study, Shao et al developed a TNF alpha containing PEG conjugates of GNSPs.30 An in vivo photothermal tumour ablation capacity (on SCK cells on A/J mice) of GNSP was comparatively tested with standalone lasers of 532 nm and 690 nm individually on test groups (test groups: the plain laser, combined GNSP-TNF, and GNSP-PEG conjugate). The gene discussed is TNF; the disease is neoplasm.