Region of residence, BMI, albumin, transferrin saturation, ferritin, vitamin D3, sodium, calcium, creatinine, urea, hemoglobin, glycosylated hemoglobin (HbA1c), number of prescribed drugs, substance dependence, power grip strength (PGS), slow walking time (SWT), low physical activity (LPA), self-reported exhaustion (SRE), unintentional weight loss (UWL), and erythrocyte sedimentation rate (ESR) were independent significant predictors of frailty (Table 4). Here, TF is linked to substance dependence.