Our study reported the high serum levels of glycated albumin, glycated albumin (per cent) and angiopoietin two in type two diabetics with diabetic retinopathy as compared to non-retinopathy diabetics with significant differences (p=0.003, p=0.001 and (p=0.033) respectively, for GA, GA (per cent) and ANG-2). The gene discussed is ALB; the disease is retinal disorder.