A study has revealed that Prx2 can effectively remove hydrogen peroxide and avoid tissue and cell damage caused by oxidative stress.20 ET-1, an endogenous vasoactive substance synthesized and released by vascular endothelial cells, has a strong vasoconstrictive function and plays a very important role in the pathogenesis and development of multiple vascular diseases.21 Clinically, SAH is usually induced by rupture and hemorrhage of intracranial aneurysms. This evidence concerns the gene EDN1 and Dilatation of the cerebral artery.