Eleven of these genes appeared significantly increased in male PD patients (AC073283.7, ATP5J2-PTCD1, GPR4, IL15RA, ITGA5, LAMA5, MAP3K6, MEGF6, PNTM, PRDM12, and RASIP1), with the majority associated with oxidative stress, inflammation, and cerebral disorders [81]. Here, GPR4 is linked to Parkinson disease.