(Fig. 6, Additional file: 3) In the gene profiles of periodontitis, MYOZ2 is significantly positively correlated to ATP Binding Cassette Subfamily B Member 1 (ABCB1), the biomarker of Type 17 T help cells, Caspase 3 (CASP3), the biomarker of effector memory CD4 T cell, CD36 Molecule (CD36), the biomarker of Gamma delta T cell, and many other biomarkers of adaptive immune cells and innate immune cells. This evidence concerns the gene CD4 and periodontitis.