PLAU and metastatic malignant neoplasm in the lymph nodes: They performed a retrospective study on the expression of bikunin, uPA and CD68 (macrophages) in 89 tumor specimens, evidencing that i) bikunin localized mainly in the cytoplasm of tumor-infiltrating macrophages, ii) its levels were inversely related with those of uPA, iii) low expression of bikunin was inversely related with lymph node metastasis and disseminated peritoneal metastasis.