CD40LG and plasma cell myeloma: In brief, the criteria include less than 10% clonal plasma cells in the BM, serum monoclonal protein (non-IgM type) < 30 g/L, or abnormal free light ratio (< 0.26 or > 1.65) and urinary monoclonal protein < 500 mg/24 h in light chain MGUS (approximately 20% of cases), absence of myeloma-defining end-organ damage such as hyperCalcaemia, Renal insufficiency, Anemia, and Bone lesions (so-called CRAB criteria), or amyloidosis that can be attributed to the plasma cell clone.