CSF3 and Decreased total neutrophil count: Diarrhea AEs of interest were more frequent in the abemaciclib subcohort (9.8%) compared with the palbociclib subcohort (1.5%), whereas neutropenia events that required G-CSF drugs were more common in the palbociclib subcohort (5.1%) compared to the abemaciclib subcohort (3.0%; Table 7).