GFAP and fleck corneal dystrophy: To further verify the involvement of the astrocytic Na+-K+-ATPase in the anti-seizure effects of astrocyte stimulation in FCD rats, we injected FCD-ChR2M1 rats with a Na+-K+-ATPase α2 shRNA driven by the GFAP promoter to selectively knockdown astrocytic Na+-K+-ATPase expression (Fig. 6k, l).