A systematic review and meta‐analysis reported that cerebrospinal fluid (CSF) and plasma oxytocin levels were not altered in patients with schizophrenia, BD, or MDD compared with those in healthy controls,32 whereas the association of oxytocin with social anxiety or socio‐emotional behavior has been suggested in patients with schizophrenia and MDD.25, 26. This evidence concerns the gene OXT and major depressive disorder.