It is worth to mention that a few genes with a role in acute myeloid leukemia: GRB2, CSFIR, MARCKS and PDGFB were upregulated; FLT1, IL6, PIK3C2B, BALAP3 and MAPK10 were downregulated (Fig 7B–7D). Here, GRB2 is linked to acute myeloid leukemia.