In that report, the small sample size did not allow an association with cognitive impairment (21), but future studies should be informative, although the use of oligonucleotide-labeled monoclonal antibodies to formally identify CD4+ T cells vs. other cell types will be required, as their transcripts of CD4 were not always detected by scRNAseq (21). The gene discussed is CD4; the disease is Cognitive impairment.