Moreover, while high p-AKT expression was positively correlated with poor overall survival in patients with lung adenocarcinoma, coordinated activation of KRAS (p-AKThi) and CD47 further increased the probability of a poor prognosis (Supplemental Figure 13, D and E; HR, 1.81 vs. 1.46). Here, AKT1 is linked to lung adenocarcinoma.