Mechanistically, insulin-producing cells (IPCs) with reduced chico levels overproduce Drosophila Insulin-like peptide 2 (Dilp2), which causes hyperinsulinemia and remotely activates insulin-TOR signalling in scrib mutant clones, thereby evading cell competition by increasing intracellular protein synthesis [62] (Figure 3a). Here, INS is linked to Hyperinsulinemia.