F10 and ischemic stroke: Use of FXa inhibitor was associated with an absolute risk decrease of 0.78 (95% CI, 0.63-0.94) per 100 patient-years for ischemic stroke or systemic embolism and 0.78 (95% CI, 0.63-0.93) per 100 patient-years for major bleeding compared with use of warfarin (eTable 4 in the Supplement).