The one patient without autopsy had negative 14-3-3, and total Tau, but a positive MRI and CSF RT-QuIC, meeting UCSF, European 2009, and European 2017 probable sCJD criteria.23 Sporadic CJD molecular subtypes included one patient with MM (not pathology proven), three with MM1, three with MV1-2, two with MV2, one with VV1-2, and two with VV2. Here, MAPT is linked to Creutzfeldt Jacob disease.