The same five patients (MGH105, MGH114, MGH143, ND2, and ND4) had higher enrichment scores and proportions of cancer cells, assigned to the astrocytic signature (‘AC’) compared to the OPC signature, and the same held true for MGH115, MGH118, MGH124, MGH125, ND1, and ND6. Here, MT-ND4 is linked to cancer.