A comprehensive viral miRNA detection in children with CAEBV, EBV-HLH and EBV+ NPC suggested the abundant vial miRNA expression of BART1-5p, 3-3p, 4-5p, 6-3p, 7-3p, 13-3p, 15, 16, and 19-3p. This evidence concerns the gene ARL2BP and hemophagocytic syndrome.