ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive: Cytogenetic aberrations, such as double t(9;22)/Ph chromosome, trisomy chromosome 8, i(17q), trisomy chromosome 19, t(3;21) and t(7;11), and molecular alterations, including TP53 mutations, RAS mutations and increased BCR::ABL1 transcript levels, are pathogenetically correlated with the progression of CML [2, 3].