In order to identify upregulated genes in IDH1-mut AML that contribute to IDH1-driven leukemogenesis, we analyzed differential gene expression between patients with IDH1-wt (n = 153) and IDH1-mut (n = 28) AML with hotspot R132 mutation within the BeatAML RNA-Seq dataset [15]. The gene discussed is IDH1; the disease is acute myeloid leukemia.