While clinical trials of radiotherapy and CD47 blockade have not yet been pursued, we observed potential abscopal responses in a patient with SCLC treated with radiotherapy and M7824, a bifunctional fusion protein targeting the PD-L1 and transforming growth factor (TGF)-β pathway36,37 (Extended Data Fig. 9a,b). This evidence concerns the gene CD47 and small cell lung carcinoma.