Prior to the meeting, a review of relevant literature concerning GPV in PALB2, RAD51C, RAD51D and BRIP1 was undertaken, and a background document circulated summarising published evidence for associated cancers, cancer risks, surveillance and risk-reducing surgery (background document available via https://www.ukcgg.org/information-education/ukcgg-consensus-meetings/). This evidence concerns the gene BRIP1 and cancer.