Furthermore, other androgens are usually not elevated in ovarian hyperthecosis, whereas androgen-producing adrenal tumors are associated with high levels of DHEAS and A4, and ovarian tumors with high levels of inhibin B. Almost all women with ovarian hyperthecosis have obesity and insulin resistance, but this is not the case of women with an androgen-producing tumor. This evidence concerns the gene SULT2A1 and adrenal gland neoplasm.