CD274 and neoplasm: To study whether PD-L1 expression on tumor cells affects the effector functions of TRuC T cells, PD-L1 overexpressing SUIT-2-MSLN-PDL-1 and MIA PaCa-MSLN-PDL-1 (Supplementary Figure 1a) were co-cultured with TRuC T cells for up to 110 h.