Across all CD participants, age was 31.0(18–68)years (median,range) with a disease duration of 7.5(1–40)years, and C-reactive protein (CRP) of 5(5-224)mg/dl, faecal calprotectin (FCP) 434(18-1800)μg/g, Harvey-Bradshaw Index (HBI) 3(0–9), IBD fatigue score 12.0 (0–15), abdominal pain score 2.0(0–50), TNFα 3.96(0-1234)pg/ml, IL-6 34.8(0-259)pg/ml and IL-1β 1.25(0-1955)pg/ml. The gene discussed is IL1B; the disease is inflammatory bowel disease.