SLC2A5 and squamous cell carcinoma: Squamous cell cancers (derived from basal cells) frequently show elevation of GLUT1 but adenocarcinomas (which potentially arise from type II alveolar cells/club cells) were shown to elevate GLUT5 a fructose transporter and SGLT2, a transporter normally restricted to the kidney and for which there is little evidence in the normal lung (26, 37).