As shown in Fig. 1B, compared with rats in the control group, the model group rats that were intoxicated by ANIT showed a remarkable increase in the levels of the sensitive indices of liver damage (ALT and aspartate transaminase [AST]) and crucial indices of cholestasis (ALP, total bilirubin [BIL-T], direct bilirubin [BIL-D], TBA, and GGT). The gene discussed is GPT; the disease is cholestasis.