IL1B and infection: At later stages of coincubation (16 h), both LDH and IL-1β levels in the BMDCs infected with the ktr3Δ cap6Δ mutant were increased almost to the levels seen with the incubation with the WT C. neoformans cells (Fig. 8B), indicating that nonpyroptotic host cell lysis occurs at the late stage of infection without association with O-mannosylation.