IL1B and infection: Particularly, the reduced release of both LDH and IL-1β from BMDCs upon infection with the ktr3Δ cap6Δ mutant indicates that cryptococcal O-glycans assembled on cell surface mannoproteins contribute to host cell pyroptosis, a cell escape strategy employed by fungal pathogens, although other factors are also required for full induction of host cell pyroptosis in C. neoformans.