Further, Atad1 phenocopies Bcl2 and Bcl2l1 in the middle cerebral artery occlusion mouse model of ischemic stroke: deletion of Atad1 or Bcl2 exacerbates, and overexpression of Atad1, Bcl2, or Bcl2l1 decreases ischemic cell death (Zhang et al., 2019; Martinou et al., 1994; Parsadanian et al., 1998; Broughton et al., 2009). Here, BCL2 is linked to ischemic stroke.