IFNG and HIV-1 infection: We also performed GO analysis of the 17 IRPs in cluster 7 and found that the most represented categories were “inflammatory response,” “positive regulation of NIK/NF-kappaB signalling,” “chemokine-mediated signalling pathway,” “cellular response to lipopolysaccharide,” and “positive regulation of interferon-gamma production,” suggesting that these biological processes are altered during HIV-1 infection (Table S7).