PLEKHA4 was a prognostic marker in various TCGA cohorts, including cancers with high immunogenicity, immune infiltration, and TMB, including pancreatic adenocarcinoma, breast cancer, thyroid carcinoma, and hepatocellular liver carcinoma (including LGG, Figure 1(i)). This evidence concerns the gene PLEKHA4 and pancreatic adenocarcinoma.