INS and cancer: More notably, the KEGG enrichment results also revealed that the regulation of prolactin signaling pathway, pathways in cancer, endocrine resistance, EGFR tyrosine kinase inhibitor resistance, proteoglycans in cancer, central carbon metabolism in cancer, ErbB signaling pathway, insulin resistance, and cAMP signaling pathway contributed to the therapeutic effects of HHAE against OVA-induced asthma (Figure 3).