AKT1 and cancer: Moreover, among the top 20 pathways, cancer pathway, PI3k-Akt signaling, axon guidance, focal adhesion, and regulation of actin cytoskeleton were abundant while the other related pathways were involved in thyroid and oxytocin hormone signaling, synaptic vesicle cycle, adhere junction, circadian entertainment, etc. These findings are in agreement with the previous study of Deng et al. [55].