These mice also showed a significant decrease in the expression of catenins (α-, β-, γ-, and p120-) and GJ proteins (Cx40 and Cx43), resulting in slow conduction, spontaneous ventricular arrhythmias, and sudden death (Kostetskii et al., 2005; Li et al., 2006). The gene discussed is CTNND1; the disease is Ventricular arrhythmia.