The expression of ECM1 is much higher in a variety of tumor tissues, such as ovarian cancer (Yin et al., 2021), CRC (Long et al., 2022), breast cancer (Steinhaeuser et al., 2020), gastric cancer (Wu et al., 2014; Liu et al., 2019), etc., when compared with normal tissues. The gene discussed is ECM1; the disease is breast cancer.