The roles of 13 cuproptosis-related genes (FDX1, LIPT1, LIAS, DLD, DLAT, PDHA1, PDHB, DBT, GCSH, DLST, SLC31A1, ATP7A, ATP7B) in HCC were investigated (Table S3). This evidence concerns the gene FDX1 and hepatocellular carcinoma.