Although BMF/MDS are very heterogeneous, the same genomic mutations are frequently found in MDS patients such as mutations in genes related to RNA splicing (SF3B1, SRSF2, U2F1, ZRSR2), DNA methylation (TET2, DNMT3A, IDH1/IDH2), chromatin modification (ASXL1, EZH2), transcription regulation (RUNX1, BCOR), and DNA repair control (p53). Here, IDH1 is linked to myelodysplastic syndrome.