However, the observed changes in MRI might be similar to the changes in certain pathological features, as assessment of the changes in diffusion-weighted imaging has already been found to correlate with the Ki67 proliferation status in a mouse model of rhabdomyosarcoma (61) and has been found useful to predict histological markers such as Ki67 in the breast cancer xenografts MCF-7 and MDA-MB-231 (62). This evidence concerns the gene MKI67 and breast carcinoma.