Of the 17 DDR genes found to be related to prognosis of NSCLC patients, high expression of 8 genes (ATRIP, DDB2, REV1, RPA2, NFATC2IP, NSMCE4A, RAD1, and XAB2) contributed to good overall patient outcome, and high expression of 9 genes (RECQL, RRM2, XRCC5, CDC25C, DCLRE1B, GADD45A, H2AFX, NBN and NEIL3) was indicative of poor prognosis. The gene discussed is XRCC5; the disease is non-small cell lung carcinoma.