Frequencies of LDHC in pan-cancer: melanoma (7/16), breast (7/20), colon (3/20), prostate (3/8), lung (8/17), kidney (4/7), ovary (3/7), thyroid (1/4), and cervix (5/6); melanoma cell lines (5/8) and lung cancer cell lines (2/6); LDHC activation was neither mediated by gene promotor demethylation nor induced by hypoxia. The gene discussed is LDHC; the disease is cancer.