VEGF denotes a group of signal proteins that promote blood vessel formation or angiogenesis (Senger et al., 1983; Ferrara et al., 2003; Gogat et al., 2004) that have been studied in various diseases (Ellis and Hicklin, 2008) as their main inhibitor (anti-VEGF) could reduce the severity of many pathological conditions, including wet AMD (Schmidt-Erfurth et al., 2014). Here, VEGFA is linked to wet macular degeneration.