SHBG and Infertility: The menstrual pattern is influenced by thyroid hormones directly through impact on the ovaries and indirectly through impact on sex hormone binding globulin (SHBG), prolactin and gonadotrophin releasing hormone (GnRH) secretion and coagulation factors.2 Previous studies have suggested that subclinical hypothyroidism is one of the important thyroid dysfunctions resulting in infertility and may be associated with ovulatory dysfunction.6,7,8 The reported prevalence of subclinical hypothyroidism among unselected infertile women was 14% 9 against the 2–4% reported among the general population.10