Another study reported that METTL3 could interact with the CAATT-box binding protein CEBPZ on target transcripts and mediate m6A modification to promote the translation of target mRNAs that maintain the leukaemic state in acute myeloid leukaemia (AML) cells (Barbieri et al., 2017). This evidence concerns the gene CEBPZ and acute myeloid leukemia.