Furthermore, pericyte FAK deletion enhances Gas6-stimulated phosphorylation of the receptor tyrosine kinase Axl and upregulates Cyr61, while pericyte-derived Cyr61 indicates that tumor cells upregulate the expression of the pro-angiogenic/tumorigenic transmembrane receptor tissue factor (Lechertier et al., 2020b). Here, CCN1 is linked to neoplasm.