For early diagnosis of nasopharyngeal carcinoma, Hu et al. recently combined EVs expressing the EBV-encoded membrane proteins LMP1 and LMP2A with EVs expressing other tumor marker proteins as liquid biopsy markers and significantly outperformed the traditional VCA-IgA assay in distinguishing patients with NPC from healthy donors and patients with nasopharyngitis, with accuracies of 96.3% and 83.1%. This evidence concerns the gene PDLIM7 and nasopharyngeal carcinoma.